Peptide GuideTB-500

The Peptide Guide

All healing & recovery peptides

TB-500

HealingRecovery

TB-500 is a synthetic peptide related to thymosin beta-4. It is investigated in preclinical research for cell migration, blood vessel formation, inflammation signaling, and tissue repair.

What does it do?

Supports whole body recovery after training or strain
Can reduce stiffness and help movement feel easier
Aids soft tissue repair across muscles, tendons, and connective tissue
Helps the body bounce back between sessions
Is used more for overall recovery than for one isolated spot
May support flexibility and comfort as tissue remodeling picks up

How does it work?

Is a fragment of thymosin beta-4, a protein already involved in repair
Helps cells move to where they are needed after injury
Supports new blood vessel growth in damaged tissue
Aids actin regulation, which cells use to migrate and rebuild
Lowers some inflammatory signaling so repair can proceed more cleanly
Spreads more systemically than a local gut peptide, which is why it feels bodywide

What to expect?

The whole body can feel less stiff after training or a long day
Bounce back between sessions feels a little quicker than you are used to
It is less “this one joint is suddenly fine” and more “I feel less beat up overall”
Tight spots may loosen enough that warmups feel easier
That sense of ease tends to build across a cycle rather than after one dose

How it's typically administered

Sub-Q injectionSubcutaneous injectionmost common route in research

How it's typically dosed

Most common dose2–2.5 mg
FrequencyTwice weekly (loading); every 1–2 weeks (maintenance)
Cycle duration4–6 weeks loading

BackAll healing & recovery peptides Full peptide list