Peptide GuideLL-37

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LL-37

Immune supportHealing

LL-37 is the human cathelicidin antimicrobial peptide. It is studied for innate defense, biofilms, and wound support. It can irritate tissue at higher doses.

What does it do?

Is the human cathelicidin peptide used in innate immune defense
Disrupts microbial membranes and can break down biofilms
Also signals wound-repair and immune-cell pathways
Used for immune and local infection support, not muscle
Can irritate host tissue at higher concentrations
Short cycles are used because the peptide is biologically sharp

How does it work?

Disrupts microbial membranes
Also signals immune cells and wound-repair paths
Can hit host cells if the dose is high, which is why irritation happens
Works locally and systemically
Not an antibiotic replacement on its own
Vitamin D status affects the body's own LL-37 production

What to expect?

The pin can burn more than BPC
The site can stay red for a while
There is no boosted feeling
Irritated tissue can settle over the cycle
Higher doses make the sting worse first

How it's typically administered

Sub-Q injectionSubcutaneous injection
Topical gel or creamTopical gel or creamon wounds in research settings

How it's typically dosed

Most common dose100–200 mcg
FrequencyOnce daily
Cycle duration2–6 weeks, then time off

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