The Peptide Guide logoPeptide GuideGHK-Cu

GHK-Cu

CollagenSkin repair

GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma. Levels decline with age, and it is one of the most widely studied peptides in skin and wound-healing research.

What does it do?

  • Promotes collagen and elastin so skin can look firmer and more elastic
  • Supports tissue remodeling after wear, injury, or aging

How does it work?

  • Binds copper and delivers it to enzymes that rebuild tissue
  • Turns on genes tied to collagen, elastin, and matrix repair

What to expect?

  • Skin can feel a bit firmer and look more even as the weeks go by
  • Fine lines tend to soften slowly instead of vanishing right away

How it's typically administered

  • Sub-Q injectioncommon in research settings
  • Topical serum or creamwidest cosmetic use
  • Nasal sprayless common; limited absorption data
  • Oral capsulesbioavailability is debated

How it's typically dosed

  • Most common dose1–2 mg
  • Frequency5 days a week
  • Cycle duration10–12 weeks