GHK-Cu
CollagenSkin repair
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma. Levels decline with age, and it is one of the most widely studied peptides in skin and wound-healing research.
What does it do?
- Promotes collagen and elastin production, supporting tissue remodeling
- Reduces fine lines, improves skin firmness and elasticity
How does it work?
- Binds copper ions to help regulate tissue repair and collagen remodeling genes
- Upregulates antioxidant defenses and extracellular matrix remodeling pathways
How it's typically administered
- Subcutaneous injectioncommon in research settings
- Topical serum or creamwidest cosmetic use
- Nasal sprayless common; limited absorption data
- Oral capsulesbioavailability is debated
- Intramuscular injectionunnecessary and higher risk
How it's typically dosed
- Most common dose1–2 mg
- Frequency5 days a week
- Cycle duration10–12 weeks
